Signs of Alzheimers noticeable as early as age 20
Evidence of Alzheimer’s disease can be seen in people as early as age 20, indicates new research from Northwestern University, though this does not mean…
Evidence of Alzheimer’s disease can be seen in people as early as age 20, indicates new research from Northwestern University, though this does not mean all people are at risk for the disease.
According to a team of experts led by Changiz Geula, amyloid protein–the protein that eventually causes synapse-blocking plaque buildup in the brain–starts accumulating just after the teen years are over and continues to worsen with age. It’s something that can be detected with the proper medical exams.
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“It was the age that really that surprised us, Geula told Yahoo Health. In the young adults, we already see accumulation of amyloids.
The difference between the old and the young, he explained, was that amyloid clumping, the real issue in Alzheimer’s disease, was more profound in older individuals.
“What this means is these neurons are susceptible to accumulate at a young age, but that the clumping really occurs during the aging process,” said Guela. “During life, the substance needed to make clumps is available. And if you have susceptibility to form clumps, this could worsen.
The presence of amyloid protein alone is not as concerning as the formation of clumps. The Alzheimer’s Association indicates amyloid proteins naturally form plaques because they are sticky by nature. When these plagues clump together, they block cell-to-cell signaling at synapses and also trigger the body’s immune system, causing inflammation and the deterioration of brain cells.